- I have just been reading about this 'warning' on hoax-slayer, and the saddest thing is that even though the hoax is explained in detail there are still comments where people express belief. Amy, yes the brown recluse bite can cause tissue damage, it is unusual. Very often necrosis is diagnoses as a spider bite when there is no evidence to support this. In fact, many spider bite diagnosis have been shown to be mistaken. There is no confirmed case of the brown recluse causing death so please add documentation including your friends name, the attending doctor, the hospital where this happened etc. Lets all be a little more serious and responsible.