Australian Museum Journal Anti-retroviral drugs and vaccines

Shortform:
Levy and Lifson, 2014. Tech. Rep. Aust. Mus., Online 24: 93–95
Author(s):
Laura S. Levy; Jeffrey D. Lifson
Year published:
2014
Title:
Anti-retroviral drugs and vaccines
Serial title:
Technical Reports of the Australian Museum (online)
Volume:
24
Start page:
93
End page:
95
DOI:
10.3853/j.1835-4211.24.2014.1625
Language:
English
Date published:
29 May 2014
Cover date:
29 May 2014
ISSN:
1835-4211 (online)
Publisher:
The Australian Museum
Place published:
Sydney, Australia
Subjects:
RETROVIRUS; ANIMAL DISEASE; VIROLOGY; MAMMALIA: MARSUPIALIA
Digitized:
29 May 2014
Available online:
29 May 2014
Reference number:
1625
EndNote package:
EndNote file
Title page:
Title page (160kb PDF)
Complete work:
Complete work (311kb PDF)

Abstract

This manuscript summarizes the break-out session held on anti-retroviral drugs and vaccines at the Koala Conservation Workshop: The koala and its retroviruses: implications for sustainability and survival held at San Diego Zoo, April 17–18, 2013. Discussants considered the utility of natural retroviral systems as models for treatment and prevention of koala retrovirus (KoRV) infection, in particular, feline leukemia virus infection of the cat and AIDS virus infections of humans and non-human primates. Key lessons learned from those model systems may be applicable to the development of anti-retroviral drugs for treatment of KoRV infection or vaccines to prevent it. Aspects of the experience with model systems that are most likely to be translatable to KoRV infection include the identification of optimal drug targets, parameters for drug delivery, components of an effective vaccine, and approaches to measure protection.