Australian Museum Journal Koala retrovirus (KoRV): molecular biology and evolution

Shortform:
Greenwood and Roca, 2014. Tech. Rep. Aust. Mus., Online 24: 11–14
Author(s):
Alex D. Greenwood; Alfred L. Roca
Year published:
2014
Title:
Koala retrovirus (KoRV): molecular biology and evolution
Serial title:
Technical Reports of the Australian Museum (online)
Volume:
24
Start page:
11
End page:
14
DOI:
10.3853/j.1835-4211.24.2014.1607
Language:
English
Date published:
29 May 2014
Cover date:
29 May 2014
ISSN:
1835-4211 (online)
Publisher:
The Australian Museum
Place published:
Sydney, Australia
Subjects:
RETROVIRUS; ANIMAL DISEASE; VIROLOGY; MAMMALIA: MARSUPIALIA
Digitized:
29 May 2014
Available online:
29 May 2014
Reference number:
1607
EndNote package:
EndNote file
Title page:
Title page (159kb PDF)
Complete work:
Complete work (803kb PDF)

Abstract

The koala retrovirus (KoRV) is in transition between occurring as an exogenous retrovirus spread by infection and becoming an endogenous retrovirus spread primarily as part of the host germ line. While up to 10% of mammalian genomes are composed of such endogenous retroviruses (ERVs), KoRV is the only known example of a retrovirus in the process of making this transition. Thus, it presents a singular opportunity to study the host-pathogen interactions involved during retroviral invasion of a vertebrate germ line.

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